講座主題：Sequestration of a transposon-derived siRNA by a target mimic imprinted gene induces postzygotic reproductive isolation in Arabidopsis
專家姓名： 王桂鳳
工作單位：河南農(nóng)業(yè)大學(xué)
講座時間：2018.7.22上午9:30
講座地點(diǎn)：海院329
主辦單位：煙臺大學(xué)海洋學(xué)院
內(nèi)容摘要：
Genomic imprinting is an epigenetic phenomenon occurring in mammals and flowering plants causing genes to be expressed depending on their parent-of-origin. In plants, genomic imprinting is mainly confined to the endosperm, a nutritive tissue supporting embryo growth, similar to the placenta in mammals. Here we show that the paternally expressed imprinted gene PEG2 transcript is a small RNA sponge and sequesters the transposable element-derived small interfering RNA siRNA854 in the endosperm. SiRNA854 is present in the vegetative cell of pollen and transferred to the central cell of the female gametophyte after fertilization, where it is captured by PEG2. Depletion of siRNA854 as a consequence of increased PEG2 transcript levels establishes a reproductive barrier and prevents successful hybridizations between plants differing in chromosome number (ploidy). Thus, the balance of a male gamete accumulating TE-derived siRNA and a paternally-expressed imprinted gene regulate triploid seed viability, revealing a transgenerational epigenetic speciation mechanism.
主講人介紹：
王桂鳳，教授，博士生導(dǎo)師，省部共建小麥玉米作物學(xué)國家重點(diǎn)實(shí)驗(yàn)室玉米籽粒研究方向的學(xué)術(shù)帶頭人。2008年博士畢業(yè)于南京林業(yè)大學(xué)，隨后受聘上海大學(xué)生命科學(xué)學(xué)院從事玉米分子遺傳學(xué)研究；2014年至2016年在瑞典農(nóng)業(yè)大學(xué)Claudia K?hler院士實(shí)驗(yàn)室從事擬南芥種子發(fā)育的表觀遺傳調(diào)控研究；2017年11月作為特聘教授引進(jìn)到河南農(nóng)業(yè)大學(xué)農(nóng)學(xué)院工作；2009年江蘇省優(yōu)秀博士論文獲得者，2017年獲得上海市浦江人才計劃，2018年獲得河南省科技創(chuàng)新杰出青年。主要從事玉米和擬南芥胚和胚乳發(fā)育的遺傳和表觀遺傳調(diào)控，倍性間及種屬間生殖障礙的分子機(jī)制研究。主持國家級項目3項，省部級項目5項。以第一作者（或者共同一作）或通訊作者在Developmental Cell, Plant Cell, New Phytologist, Plant Biotechnology Journal和Journal of Experimental Botany等學(xué)術(shù)雜志上發(fā)表SCI論文多篇。
